📂 Diseases
autoimmune hemolytic anemia — Definition
Otoimmün hemolitik anemi / autoimmune hemolytic anemia
Otoimmun hemolytic anemia is a developing blood disease, as the result of the immune system to accidentally target antibodies to their red blood cells. This condition leads to early destruction (hemoliz) in the narrow and other organs of red blood cells. The disease can be classified depending on hot or cold antibody types and manifests itself with symptoms such as fatigue, paleness, yellowness and darkening in urine color. Corticosteroids in the treatment are used immunosuppressive drugs and splenectomy ( surgical removal of the skin).
Disease Definition
🔬 Disease Definition
Otoimmün hemolitik anemi (AIHA), vücudun bağışıklık sisteminin kendi kırmızı kan hücrelerine karşı antikorlar üretmesi sonucu bu hücrelerin erken yıkımına (hemoliz) yol açan bir hastalıktır.
🧬 Causes & Risk Factors
Primer (idiyopatik) veya sekonder (lenfoproliferatif hastalıklar, otoimmün hastalıklar, ilaçlar, enfeksiyonlar gibi tetikleyicilere bağlı) olabilir.
🩺 Symptoms & Signs
Yorgunluk, solukluk, sarılık, koyu renkli idrar, ateş, splenomegali, taşikardi, nefes darlığı.
📋 Diagnostic Methods
Tam kan sayımı (anemi, retikülositoz), direkt Coombs testi (pozitif), periferik yayma (sferositler), indirekt bilirubin ve LDH yüksekliği.
💊 Treatment Options
Kortikosteroidler (prednizon), immünosupresifler (rituksimab, siklofosfamid), splenektomi, destek tedavisi (folik asit, kan transfüzyonu).
⚠️ Complications
Hemolitik kriz, tromboembolik olaylar, splenomegali, kalp yetmezliği, böbrek hasarı.
Frequently Asked Questions
❓ What is Otoimmün hemolitik anemi?
Otoimmün hemolitik anemi; otoimmun hemolytic anemia is a developing blood disease, as the result of the immune system to accidentally target antibodies to their red blood cells. This condition leads to early destruction (hemoliz) in the narrow and other organs of red blood cells. The disease can be classified depending on hot or cold antibody types and manifests itself with symptoms such as fatigue, paleness, yellowness and darkening in urine color. Corticosteroids in the treatment are used immunosuppressive drugs and splenectomy ( surgical removal of the skin).
❓ What is autoimmune hemolytic anemia in Turkish?
The Turkish equivalent of "autoimmune hemolytic anemia" is Otoimmün hemolitik anemi.
❓ Which medical field is Otoimmün hemolitik anemi related to?
This term belongs to the Diseases category.