📂 Anatomy
isocitrate dehydrogenase complex (NAD+) — Definition
İzositrat dehidrogenaz kompleksi (NAD+) / isocitrate dehydrogenase complex (NAD+)
Isocytes dehydrogenase complex (NAD+), tricarboxylic acid cycle (Krebs cycle) is an enzyme complex that catalyzes the alpha-ketoglutarata oxidative decarboxylation. During this reaction, NAD+ is formed by reducing NADH and contributes to cellular energy production. Clinical significance is often seen in cancers such as IDH1 and IDH2 gene mutations gliom and acute myelloid leukemia, which leads to the accumulation of mutations oncometabolite 2-hydroxyglutarate.
Frequently Asked Questions
❓ What is İzositrat dehidrogenaz kompleksi (NAD+)?
İzositrat dehidrogenaz kompleksi (NAD+); isocytes dehydrogenase complex (NAD+), tricarboxylic acid cycle (Krebs cycle) is an enzyme complex that catalyzes the alpha-ketoglutarata oxidative decarboxylation. During this reaction, NAD+ is formed by reducing NADH and contributes to cellular energy production. Clinical significance is often seen in cancers such as IDH1 and IDH2 gene mutations gliom and acute myelloid leukemia, which leads to the accumulation of mutations oncometabolite 2-hydroxyglutarate.
❓ What is isocitrate dehydrogenase complex (NAD+) in Turkish?
The Turkish equivalent of "isocitrate dehydrogenase complex (NAD+)" is İzositrat dehidrogenaz kompleksi (NAD+).
❓ Which medical field is İzositrat dehidrogenaz kompleksi (NAD+) related to?
This term belongs to the Anatomy category.