📂 Anatomy
P-TEFb complex — Definition
P-TEFb kompleksi / P-TEFb complex
Positive transcription factor b (P-TEFb) complex is a protein complex that is located in the cell nucleus and regulates the transcription elongation of RNA polymerase II. Siklin addicted kinaz consists of 9 (CDK9) and cyclolin T1 or T2 subunits. This complex allows RNA polymerase II to pass the carboxyl-terminal domain from the beginning stage of the transcription. Clinically, the dysregulation of the P-TEFb complex is associated with diseases such as cancer, HIV reapplication and cardiac hypertrophy.
Frequently Asked Questions
❓ What is P-TEFb kompleksi?
P-TEFb kompleksi; positive transcription factor b (P-TEFb) complex is a protein complex that is located in the cell nucleus and regulates the transcription elongation of RNA polymerase II. Siklin addicted kinaz consists of 9 (CDK9) and cyclolin T1 or T2 subunits. This complex allows RNA polymerase II to pass the carboxyl-terminal domain from the beginning stage of the transcription. Clinically, the dysregulation of the P-TEFb complex is associated with diseases such as cancer, HIV reapplication and cardiac hypertrophy.
❓ What is P-TEFb complex in Turkish?
The Turkish equivalent of "P-TEFb complex" is P-TEFb kompleksi.
❓ Which medical field is P-TEFb kompleksi related to?
This term belongs to the Anatomy category.