📂 Diseases
severe combined immunodeficiency due to IKK2 deficiency — Definition
IKK2 eksikliğine bağlı ağır kombine immün yetmezlik / severe combined immunodeficiency due to IKK2 deficiency
IKK2 (inhibitor kappa B kinaz 2) is a primary immunodeficiency disease with autozomal resessive transition, resulting in mutations in the gene. This situation significantly affects the functions of T cells, B cells and natural immune cells by turning the NF- sinyalB signal path to deterioration. Patients apply with repetitive, appealing and heavy infections in the first months of life; they are often dead if not treated. Definite diagnosis is subject to genetic tests and is the most effective option of hematopoietic stem cell transplant in the treatment.
Frequently Asked Questions
❓ What is IKK2 eksikliğine bağlı ağır kombine immün yetmezlik?
IKK2 eksikliğine bağlı ağır kombine immün yetmezlik; iKK2 (inhibitor kappa B kinaz 2) is a primary immunodeficiency disease with autozomal resessive transition, resulting in mutations in the gene. This situation significantly affects the functions of T cells, B cells and natural immune cells by turning the NF- sinyalB signal path to deterioration. Patients apply with repetitive, appealing and heavy infections in the first months of life; they are often dead if not treated. Definite diagnosis is subject to genetic tests and is the most effective option of hematopoietic stem cell transplant in the treatment.
❓ What is severe combined immunodeficiency due to IKK2 deficiency in Turkish?
The Turkish equivalent of "severe combined immunodeficiency due to IKK2 deficiency" is IKK2 eksikliğine bağlı ağır kombine immün yetmezlik.
❓ Which medical field is IKK2 eksikliğine bağlı ağır kombine immün yetmezlik related to?
This term belongs to the Diseases category.