📂 Diseases
glucocorticoid-remediable aldosteronism — Definition
Glukokortikoidle Düzeltilebilir Aldosteronizm / glucocorticoid-remediable aldosteronism
Fixable aldosteronism with Glucocorticoid is a rare cause of hereditary hypertension, characterized by excessive production of aldosterone in the adrenal glands. This situation is often caused by kimeric gene fusion between CYP11B1 and CYP11B2 genes and leads to an abnormal enzymeatic activity. Early start in patients, severe hypertension and low potassium levels (hyokalemi). As the name suggests, this condition can be corrected with glucocorticoid therapy (e.g. decanoate), because these drugs print abnormal aldosterone production.
Frequently Asked Questions
❓ What is Glukokortikoidle Düzeltilebilir Aldosteronizm?
Glukokortikoidle Düzeltilebilir Aldosteronizm; fixable aldosteronism with Glucocorticoid is a rare cause of hereditary hypertension, characterized by excessive production of aldosterone in the adrenal glands. This situation is often caused by kimeric gene fusion between CYP11B1 and CYP11B2 genes and leads to an abnormal enzymeatic activity. Early start in patients, severe hypertension and low potassium levels (hyokalemi). As the name suggests, this condition can be corrected with glucocorticoid therapy (e.g. decanoate), because these drugs print abnormal aldosterone production.
❓ What is glucocorticoid-remediable aldosteronism in Turkish?
The Turkish equivalent of "glucocorticoid-remediable aldosteronism" is Glukokortikoidle Düzeltilebilir Aldosteronizm.
❓ Which medical field is Glukokortikoidle Düzeltilebilir Aldosteronizm related to?
This term belongs to the Diseases category.