📂 Diseases
MDR1 multiple drug sensitivity — Definition
Çoklu İlaç Duyarlılığı (MDR1) / MDR1 multiple drug sensitivity
MDR1 gene mutation is a hereditary condition, especially seen in some animal species, especially in dogs. This mutation disrupts the function of a carrier protein called P-glikoprotein, located in the blood-brain barrier. As a result, some drugs such as ivermektin lead to neurological toxicity by integrating in the brain. Several symptoms such as letargia, apathy, coma and even death can occur.
Frequently Asked Questions
❓ What is Çoklu İlaç Duyarlılığı (MDR1)?
Çoklu İlaç Duyarlılığı (MDR1); mDR1 gene mutation is a hereditary condition, especially seen in some animal species, especially in dogs. This mutation disrupts the function of a carrier protein called P-glikoprotein, located in the blood-brain barrier. As a result, some drugs such as ivermektin lead to neurological toxicity by integrating in the brain. Several symptoms such as letargia, apathy, coma and even death can occur.
❓ What is MDR1 multiple drug sensitivity in Turkish?
The Turkish equivalent of "MDR1 multiple drug sensitivity" is Çoklu İlaç Duyarlılığı (MDR1).
❓ Which medical field is Çoklu İlaç Duyarlılığı (MDR1) related to?
This term belongs to the Diseases category.